| Product Category: | Mouse lentivirus expressing Sting1 |
| Description: | Premade lentivirus for over-expression of mouse Sting1 and control, ready to use format. |
| Gene Name: | stimulator of interferon response cGAMP interactor 1 |
| Gene Symbol: | Sting1 |
| Synonyms: | ERIS; MPYS; Mita; STING; Tmem173; STING-beta; 2610307O08Rik |
| ACCN: | NM_028261.1 |
| Gene ID: | 72512 |
| Vector: | pLVX-puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables 2',3'-cyclic GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to symbiont; macroautophagy; and positive regulation of innate immune response. Acts upstream of or within cellular response to interferon-beta; positive regulation of transcription by RNA polymerase II; and regulation of inflammatory response. Located in several cellular components, including Golgi membrane; autophagosome; and perinuclear region of cytoplasm. Part of STING complex. Is active in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment membrane. Is expressed in ductus deferens; epididymis; ileum; liver; and prostate gland. Used to study STING-associated vasculopathy with onset in infancy. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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